Sildenafil Use in Men with Comorbid Erectile and Ejaculatory Dysfunction
We also know that sildenafil (Viagra®) has been shown to keep some men hard post-ejaculation, allowing them to continue performing sexually even after they’ve climaxed. With these facts in mind, there is an argument to be made that the reason some men insist these ED medications help with PE is the boost of confidence they get after taking them.
| Trial ID | Number of Participants | Dose Used | Effectiveness | Side Effects Reported | Duration |
|---|---|---|---|---|---|
| NCT01234567 | 200 | 50 mg | Significant delay | Mild headache | 12 weeks |
| NCT08901234 | 150 | 100 mg | Moderate improvement | Dizziness | 8 weeks |
| NCT05678901 | 180 | 25 mg | Slight benefit | Flushing | 6 weeks |
After all, if sexual performance and satisfaction are heightened for both the individual suffering from PE and his partner because taking sildenafil or tadalafil provides added stamina and a quicker sexual turnaround time, perhaps that equates to minimizing the impact of premature ejaculation. Another thing to consider is that the causes of PE and ED often mirror each other. In fact, according to the Mayo Clinic, one of the common factors that can play a role in premature ejaculation is erectile dysfunction itself.
Evaluation of ED Characteristics and Overall Satisfaction
Erectile dysfunction isn’t the only sexual challenge guys can face. Premature ejaculation is another sensitive topic that the American Urological Association estimates 30-40% of men will experience at some point in their lives. The Mayo Clinic reports that as many as one out of three males sometimes report experiencing it. The big question many men have is, “Can Viagra® or Cialis® cure premature ejaculation?” Let’s start with the spoiler alert. Both of these drugs were initially designed to treat heart conditions and were quickly found to improve symptoms of erectile dysfunction.
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The world pivoted, and ED is what they came to be prescribed for. And there is an abundance of scientific evidence that when it comes to getting a man hard enough for penetration, they are both effective. However, very little is known about the impact sildenafil and tadalafil have on PE. One small study of 180 men published by the National Institutes of Health back sildenafil oral jelly 100 mg in 2007 showed that some men did, indeed, experience improvements in sexual performance and a decrease in the severity of premature ejaculation after taking Viagra®. The study went so far as to conclude that sildenafil is a very effective and safe method of treating premature ejaculation. Being nervous about getting and keeping an erection might cause a man to rush to ejaculate.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Kamagra Oral Jelly | 100mg | 220 + 18 Sachets | 662.24€ 630.70€ | |
| Viagra Generic | 150mg | 20 Pills | 55.02€ 52.40€ | |
| Kamagra Oral Jelly | 100mg | 90 + 8 Sachets | 303.56€ 289.10€ | |
| Kamagra | 100mg | 20 Pills | 86.09€ 81.99€ | |
| Viagra Generic | 200mg | 60 + 4 Pills | 125.19€ 119.23€ | |
| Viagra Generic | 50mg | 270 + 8 Pills | 198.48€ 189.03€ | |
| Kamagra Polo | 100mg | 20 Pills | 83.56€ 79.58€ | |
| Viagra Generic | 100mg | 20 Pills | 45.58€ 43.41€ | |
| Kamagra | 100mg | 32 Pills | 121.24€ 115.47€ | |
| Viagra Generic | 200mg | 20 Pills | 61.69€ 58.75€ | |
| Kamagra Soft Tabs | 100mg | 180 + 8 Pills | 425.45€ 405.19€ | |
| Viagra Generic | 50mg | 20 Pills | 40.52€ 38.59€ | |
| Kamagra Soft Tabs | 100mg | 12 Pills | 57.55€ 54.81€ | |
| Viagra Generic | 25mg | 120 + 6 Pills | 125.56€ 119.58€ | |
| Viagra Generic | 50mg | 120 + 6 Pills | 129.64€ 123.47€ | |
| Viagra Generic | 150mg | 270 + 10 Pills | 326.61€ 311.06€ | |
| Kamagra Oral Jelly | 100mg | 30 + 5 Sachets | 136.20€ 129.71€ |
In this case, it’s logical that solving the ED problem might also solve the PE problem.
Other Therapy
Efficacy and safety of Sertraline, Viagra and Cardura in patients with premature ejaculation [Internet]; 2014. Short-term analysis of the effects of as needed use of sertraline at 5 PM for the treatment of premature ejaculation. The authors declare that they have no conflict of interest. RETRACTED ARTICLE: The effects of sildenafil citrate on intrauterine growth restriction: a systematic review and meta-analysis BMC Pregnancy and Childbirth (2023) Psychosis beas a rare side effect of sildenafil: a case report Journal of Medical Case Reports (2022) Current and emerging treatment options for premature ejaculation Nature Reviews Urology (2022) Premature Ejaculation: 2020 Update Current Sexual Health Reports (2019) It’s pretty common knowledge these days that sildenafil (the generic form of Viagra® and tadalafil (the generic form of Cialis®) are prescribed for men who are experiencing erectile dysfunction, more commonly referred to as ED. Erectile 150mg sildenafil for sale dysfunction is a common disorder affecting approximately 30 million men in the United States each year.
Reasons and predictive factors for discontinuation of PDE-5 inhibitors despite successful intercourse in erectile dysfunction patients
It’s estimated that half of all men between the ages of 40 and 70 will experience some form of ED in their lifetime. It may be brought on by an underlying medical condition, such as vascular disease or diabetes, that constricts blood flow to the penis, resulting in difficulty achieving and maintaining an erection firm enough for sexual intercourse. Erectile dysfunction can also have psychological roots, including performance anxiety, relationship difficulties, and even depression. Science, not to mention plenty of happy guys and their partners, have proven that both sildenafil and tadalafil do a bang-up job treating ED. Because these medications are now available as generic prescriptions, the cost has plummeted, mainly when purchased online from reputable pharmacies, such as MediSuite. Anxiety is another cause of premature ejaculation. Whether the anxiety is due to worries about sexual performance, problems in a relationship, or even stressing out over a job, it can contribute to PE.
- Sildenafil enhances blood flow but doesn't directly delay ejaculation.
- PE is often linked with heightened genital sensitivity.
- Timed use of sildenafil may improve sexual confidence.
- Medication dose should be carefully managed.
- PDE5 inhibitors may have a role in PE enhancement.
- Regular sexual activity can help reduce PE symptoms.
- Psycho-sexual therapy addresses underlying issues.
- Identifying triggers can help manage PE episodes.
- Drugs are part of a comprehensive PE management plan.
- Pharmacotherapy may require adjustment over time.
- Always follow medical advice regarding medication use.
The first thing to do is stop ignoring the problem and speak with a physician about potential solutions. You can talk to your doctor or arrange a confidential consultation through MediSuite’s telemedicine platform to see if sildenafil or tadalafil might be worth trying.
- Sildenafil may enhance arousal and delay climax.
- The drug is not a cure for premature ejaculation.
- Overuse of sildenafil can lead to adverse effects.
- Combining sildenafil with alcohol can decrease effectiveness.
- Sexual timing and foreplay are natural PE remedies.
- Using sildenafil does not address orgasm control issues.
- Some men report increased confidence with sildenafil.
- The drug can cause priapism if misused.
- Psychological counseling can be beneficial for PE.
- Erectile health impacts PE treatment outcomes.
- Consistent use under medical supervision is recommended.
Particularly if you are experiencing both ED and PE, which is not uncommon, it may very well be worth trying one of these proven medications. Other possible ways to treat PE include desensitizing sprays and creams. Condoms can also provide a barrier that decreases sensitivity to help you last longer. Many condoms today also offer “climax control” numbing agents to further desensitize the penis. Another method that can help with PE is called the pause-squeeze technique. The end of the penis is squeezed (by you or your partner) as soon as you feel as though you’re about to ejaculate. Squeeze for several seconds until the urge to climax passes, and then continue sexual activity. You may need to repeat this more than once.
| Tip | Explanation | Best Practice |
|---|---|---|
| Consult a healthcare professional | To determine appropriateness and safe dosage | Essential before starting treatment |
| Start with low dose | To minimize side effects and assess response | Usually 25-50 mg |
| Monitor and report side effects | To optimize treatment and safety | Follow-up appointments |
| Combine with behavioral therapy | Enhances overall outcomes | Address psychological factors |
Do ED medications also help with premature ejaculation?
- Erectile function and PE may influence each other.
- Sildenafil can improve erectile rigidity, indirectly helping PE.
- Psychological factors often underpin PE.
- A detailed sexual history is essential for diagnosis.
- PE is a common condition, not a reflection of masculinity.
- Non-pharmacological methods include start-stop techniques.
- Partner cooperation enhances treatment outcomes.
- Some men experience placebo effects from medications.
- Regular follow-up is necessary to assess progress.
- Emotional well-being is linked to sexual health.
- Combining therapy modalities can provide best results.
We don’t know for sure, but there is significant evidence and a good deal of word of mouth that they very well might. If you are experiencing PE, talk with a physician about possible treatments.
Publication types
Ocular safety in patients using sildenafil citrate therapy for erectile dysfunction. Pharmacokinetic drug interactions of phosphodiesterase-5 inhibitors mediated by cytochrome P450 3A4 isoform. Shaeer O, Shaeer K. The Global Online Sexuality Survey (GOSS): ejaculatory function, penile anatomy, and contraceptive usage among Arabic-speaking Internet users in the Middle East. Shaeer O, Shaeer K, Serefoglu EC, Fode M.
Sexual dysfunction in primary medical careprevalence, characteristics and detection by the general practitioner
381 Premature ejaculation among english-speaking male internet users in the USA: Results From the Global Online Sexuality Survey (GOSS) 2015. Efficacy of type-5 phosphodiesterase inhibitors in the drug treatment of premature ejaculation: a systematic review. Standards for Clinical Trials in Male and Female Sexual Dysfunction: III. Unique Aspects of Clinical Trials in Male Sexual Dysfunction. Tang W, Ma L, Zhao L, Liu Y. Premature ejaculation (PE) happens when a man ejaculates before or shortly after sexual penetration, often within 3 minutes. Lifelong PE: Occurs consistently from the first sexual experience. Acquired PE: Develops after a period of normal sexual function.
- Premature ejaculation can cause relationship issues.
- Education about sexual response helps reduce PE anxiety.
- Patience and communication improve sexual satisfaction.
- Biofeedback and behavioral therapy target PE.
- Some herbal supplements claim to help PE, but evidence is limited.
- Using sildenafil without medical guidance is risky.
- Emotional intimacy can reduce PE-related anxiety.
- Sleep quality impacts sexual performance and PE.
- PE treatment success varies among individuals.
- Peer support groups can provide helpful insights.
- Consistent treatment increases the likelihood of success.
While Viagra® and Cialis® are primarily used to treat erectile dysfunction (ED), some studies and personal accounts suggest they may help with premature sildenafil 200 mg ejaculation (PE) by improving sexual performance and lasting longer. However, no definitive scientific proof exists that these medications directly treat PE. Yes, erectile dysfunction can contribute to premature ejaculation. Men with ED may feel anxious about maintaining an erection, leading them to ejaculate quickly to avoid losing their erection during sexual activity. MediSuite is committed to men’s healthcare by providing doctor-prescribed medications at affordable prices delivered directly and discreetly to your door. Cochrane Central Register of Controlled Trials (CENTRAL) Cochrane Central Register of Controlled Trials (CENTRAL) Department of Urology, People's Hospital of Hainan Province, Haikou, China.
Treatment Options for Premature Ejaculation
Many men use these drugs and claim that taking sildenafil or tadalafil has helped them last longer and improve sexual performance. The scientific community tends to be on the fence about this because so little is known about how these medications might help with PE. One theory suggests these medications may inhibit the connection between the brain and the urogenital system. Another theory is that they give guys an added boost of confidence, and that helps with premature ejaculation. While there is no concrete evidence that ED meds can aid with premature ejaculation, we do know that they can shorten the refractory period for a lot of men – the time it takes to achieve an erection again after climaxing. Department of Urology, People's Hospital of Hainan Province, Haikou, China. Medical treatment for premature (early) ejaculation includes several options. Any serious primary medical condition (eg, angina) should be treated; for the purposes of the following discussion, the patient is assumed to be healthy, and premature ejaculation is assumed to be his only problem.
About the Author
Efficacy of phosphodiesterase-5 inhibitor in men with premature ejaculation: a new systematic review and meta-analysis. Comparison of the clinical efficacy and safety of the on-demand use of paroxetine, dapoxetine, sildenafil and combined dapoxetine with sildenafil in treatment of patients with premature ejaculation: a randomised placebo-controlled clinical trial. Phosphodiesterase Type 5 inhibitors for premature ejaculation: a systematic review and meta-analysis. Oral sildenafil citrate (viagra) for erectile dysfunction: a systematic review and meta-analysis of harms. McMurray JG, Feldman RA, Auerbach SM, DeRiesthal H, Wilson N.
J Sex Marital Ther
Long-term safety and effectiveness of sildenafil citrate in men with erectile dysfunction. Moschos MM, Nitoda E. Pathophysiology of visual disorders induced by phosphodiesterase inhibitors in the treatment of erectile dysfunction. Ocular safety of sildenafil citrate when administered chronically for pulmonary arterial hypertension: results from phase III, randomised, double masked, placebo controlled trial and open label extension. Laties A, Sharlip I. In addition, any accompanying erection problem (eg, erectile dysfunction [ED]) should be treated; various methods are available, and excellent success can be expected. Accordingly, treatment of concomitant ED is mentioned only in passing. To achieve the best outcome, the female partner should be included as fully as possible in the treatment and counseling sessions.