Legal Status of Sildenafil Around the World
However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Sildenafil is a medication that is taken before sexual activity and allows men with erectile dysfunction (ED) to achieve and maintain an erection.
| Condition | Risk | Recommendation |
|---|---|---|
| Nitrate use | Severe hypotension | Do not take with nitrates |
| Heart Disease | Cardiovascular risk | Consult doctor before use |
| Kidney or Liver impairment | Altered drug metabolism | Dosage adjustment recommended |
| Retinitis Pigmentosa | Vision issues | Use with caution |
ED or impotence happens when a man is unable to achieve or maintain an erection long enough for sexual intercourse. ED can be caused by medical conditions like high blood pressure, diabetes, prostate problems, and heart disease. It can also be a side effect of the medications taken for these conditions. Personal lifestyle factors such as stress, alcohol, and/or tobacco use can also play a role. During surgery or radiation to the pelvic area (including prostate, bladder, and rectal procedures), there can be damage to the nerves that supply the penis. This can lead to either temporary or permanent impotence. Some surgeons perform "nerve-sparing" surgeries to try to preserve erectile function. Even in these cases, however, the nerves will suffer some injury, and it can take 18-24 months or longer for erectile function to return. These men should be treated aggressively with oral or injectable medications for ED in order to speed the recovery of the nerves and to prevent muscle wasting in the penis. It should be taken around 60 minutes before sex but can be taken as much as four hours or as few as 30 minutes before sex. It works for up to 4 hours. It can be taken with or without food. Your provider will sildenafil uk price find the dose that is best for you. Some men need dose changes to find the dose that works best for them. Men who take sildenafil will not have an erection without sexual stimulation. This drug is not an aphrodisiac and does not affect libido or desire. Having multiple intercourse sessions with one dose has not been studied.
Potential Side Effects and Safety Measures
This is because these drugs may cause severe low blood pressure. Be sure to tell your doctor if you take this drug. They’ll likely recommend you do not take riociguat with sildenafil. * For more details about this side effect, see the “Sildenafil: Serious side effects” section above. It’s unknown whether sildenafil is safe to take while pregnant or breastfeeding.
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Animal studies* did not show harm to the fetus when the drug was exposed to pregnant animals. However, keep in mind that animal studies don’t always reflect what will happen in humans. If you’re pregnant or can become pregnant, talk with your doctor. They’ll review the risks and benefits with you and advise whether sildenafil treatment is right for you. In certain cases, your doctor may recommend that you continue taking sildenafil during pregnancy. You should not adjust your dose without talking to your provider first. Men who take nitrates, such as nitroglycerin, Nitro-Bid, Isordil, or Deponit should not take sildenafil.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 200mg | 180 + 10 Pills | 277.56€ 264.34€ | |
| Kamagra | 100mg | 20 Pills | 86.09€ 81.99€ | |
| Viagra Generic | 50mg | 20 Pills | 40.52€ 38.59€ | |
| Viagra Generic | 100mg | 30 + 4 Pills | 60.91€ 58.01€ | |
| Viagra Generic | 150mg | 30 + 2 Pills | 72.32€ 68.88€ | |
| Viagra Generic | 150mg | 10 Pills | 36.73€ 34.98€ | |
| Viagra Generic | 25mg | 30 + 4 Pills | 47.97€ 45.69€ | |
| Viagra Generic | 50mg | 10 Pills | 26.87€ 25.59€ | |
| Kamagra Polo | 100mg | 120 + 6 Pills | 327.15€ 311.57€ | |
| Kamagra Oral Jelly | 100mg | 21 Sachets | 95.92€ 91.35€ | |
| Kamagra | 100mg | 60 + 4 Pills | 201.34€ 191.75€ | |
| Viagra Generic | 100mg | 180 + 8 Pills | 199.37€ 189.88€ | |
| Viagra Generic | 150mg | 360 + 10 Pills | 423.48€ 403.31€ | |
| Kamagra Oral Jelly | 100mg | 110 + 9 Sachets | 334.87€ 318.92€ | |
| Viagra Generic | 100mg | 10 Pills | 28.91€ 27.53€ | |
| Kamagra Oral Jelly | 100mg | 90 + 8 Sachets | 303.56€ 289.10€ |
Men who take Cardura, Flomax, or Hytrin for urinary symptoms should not take sildenafil.
| Parameter | Value | Details |
|---|---|---|
| Absorption | Rapid, within 30-60 minutes | Food can delay absorption |
| Peak Plasma Levels | 1.5 hours after intake | |
| Half-life | Approx. 4 hours | Eliminated via liver metabolism |
| Metabolization | Liver (Cytochrome P450 enzymes) | CYP3A4 major enzyme |
This medication can affect how other medications work. Be sure your provider and pharmacist know all the medications (prescription and over-the-counter) and supplements you take. Store your medication in the original, labeled container at room temperature and in a dry location (unless otherwise directed by your healthcare provider or pharmacist). This medication should not be stored in a pillbox since it should only be taken prior to sexual activity. Keep containers out of reach of children and pets.
The Company Behind Viagra
To learn how sildenafil compares with Viagra, read this article. If you’d like to learn about sildenafil and cost, see this article. For details about your condition, see our hypertension hub. You can also view our men’s health hub and this list of erectile dysfunction and premature ejaculation articles. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Ask your care team where to return any unused medication for disposal. Do not flush down the toilet or throw it in the trash. This medication may be covered under your prescription drug plan.
Understanding Sildenafil
Sildenafil may pass into breast milk, but it isn’t known how this could affect a child who is breastfed. If you are breastfeeding or planning to breastfeed, talk with your doctor. They can review the risks and benefits of taking sildenafil while breastfeeding. If you are taking sildenafil for erectile dysfunction or pulmonary arterial hypertension, it’s possible to experience side effects. Most side effects are mild to moderate in severity.
What are some side effects that I need to call my child’s doctor about right away?
If you’re experiencing symptoms of severe side blue sildenafil effects while taking sildenafil, talk with your doctor right away. If you’d like to learn more about sildenafil, talk with your doctor or pharmacist. They can help answer any questions you have about side effects from taking the drug. A generic drug and its brand-name version contain the same active ingredient, so they’re expected to have the same side effects. Referring to the following articles about sildenafil and Viagra can provide you with additional information: For details about other aspects of sildenafil, refer to this article. Patient assistance may be available to qualifying individuals without prescription drug coverage through the pharmaceutical company that makes the medication. Your care team can help you find these resources if they are available. There are a few side effects you may have while taking sildenafil. Talk to your providers if you have concerns about these side effects. Do not take a higher dose of sildenafil than your provider orders for you. Headache, facial flushing, stuffy or runny nose, and upset stomach can occur. Less frequent side effects include blurry vision, a bluish hue to the field of vision, difficulty telling the difference between the colors blue and green, sensitivity to light, or a sudden loss of vision or hearing.
- Sildenafil is a popular choice for men seeking non-invasive ED therapy.
- It's important to have realistic expectations about sildenafil's effects.
- The medication does not increase libido but improves blood flow.
- Patients should limit alcohol consumption when using sildenafil.
- It is recommended to consult a doctor if ED persists despite medication.
- Sildenafil can be used as part of a comprehensive ED treatment plan.
- The medication should be taken approximately an hour before planned activity.
- Some patients experience no side effects at prescribed doses.
- Always confirm that sildenafil is stored properly to maintain efficacy.
- Report any unusual symptoms, such as chest pain or vision loss, immediately.
If you experience any of the following while using sildenafil, you should seek immediate medical attention: An erection lasting more than 4 hours.
What happens if I miss a dose?
Certain factors can increase your risk of developing NAION during sildenafil treatment. These include previous eye conditions or coronary artery disease. They also include being age 50 years or older or smoking. Before starting sildenafil treatment, be sure to tell your doctor if you have any of these factors. They’ll help determine if the drug is right for you.
Sildenafil Tablets for ED
If you have sickle cell anemia, tell your doctor. You may have an increased risk of vaso-occlusive crisis (VOC) if you have sickle cell anemia and take sildenafil. With VOC, your blood cells block blood flow to your organs, which can be painful. Be sure to talk with your doctor if you have sickle cell anemia. They’ll advise if sildenafil is right for you. Chest, arm or neck pain, or nausea during sexual activity. Sudden loss of vision in one or both eyes, loss of hearing, ringing in the ears, or dizziness. Remember, sildenafil does not protect against sexually transmitted diseases, nor does it prevent pregnancy.
- Sildenafil helps improve erections by relaxing penile muscles.
- The drug's popularity increased rapidly after approval in the late 1990s.
- It is part of a class of medications called PDE5 inhibitors.
- Sildenafil's development marked a breakthrough for men's health.
- There are ongoing studies to expand sildenafil's therapeutic uses.
- Regular medical check-ups are advised for long-term sildenafil use.
- Generic sildenafil has made treatment more affordable worldwide.
- It’s crucial to adhere to prescribed doses to avoid adverse effects.
- The medication is often taken about 30 minutes before sexual activity.
- Using sildenafil responsibly can improve quality of life for many men.
Effective birth control is recommended during cancer treatment. Even if you are not producing sperm, you could still be fertile and conceive. Medicines that you take by mouth are called oral medicines. They're often the first line of treatment for trouble getting or keeping an erection, called erectile dysfunction (ED). Oral medicines for ED usually work well and cause few side effects. The four main medicines taken by mouth for erectile dysfunction are: They enhance the effects of a chemical the body makes that relaxes muscles in the penis, called nitric oxide. This boosts blood flow and helps you get an erection from sexual activity.
- Sildenafil is a medication used to treat erectile dysfunction in men.
- It works by increasing blood flow to the penis during arousal.
- Sildenafil is commonly sold under the brand name Viagra.
- The typical dose ranges from 25 mg to 100 mg, taken before sexual activity.
- It usually takes about 30 to 60 minutes to work after ingestion.
- Sildenafil's effects can last for up to 4-6 hours.
- It can cause side effects like headaches, flushing, and nasal congestion.
- Sildenafil should not be used with nitrate medications due to risk of dangerous drops in blood pressure.
- It is available by prescription from a healthcare provider.
- Do not take sildenafil more than once a day to avoid adverse effects.
Each oral medicine for ED has a slightly different chemical makeup. These small differences affect the way each medication works, such as how quickly it takes effect and wears off, and the possible side effects.
Drug Interactions
Conditions related to the shape of your penis. If you have conditions related to the shape of your penis, such as Peyronie’s disease, tell your doctor. These conditions may increase your risk of severe priapism* during sildenafil treatment. If you experience an erection lasting longer than 4 hours, call 911 or your local emergency number immediately. If you take nitrates for any reason.
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Taking sildenafil with drugs containing nitrates is contraindicated. (A contraindication is a factor or condition that could prevent your doctor from prescribing a drug due to risk of harm.) This is due to sildenafil’s potential to cause severe low blood pressure. * Examples of nitrates include nitroglycerin (Nitrolingual), isosorbide (Isordil), nitroprusside (Nitropress). If you take any of these drugs or any other nitrates, be sure to tell your doctor before starting sildenafil treatment. Sildenafil is contraindicated if you take a GC stimulator, including riociguat (Adempas). Your doctor or other health care professional can recommend one for you based on these factors, other health conditions you have and any other medicines you take. This medicine works best when you take it on an empty stomach an hour before sex. The body takes longer to absorb it after a high-fat meal or alcohol. Its effects often last for 4 to 5 hours. It might work longer if you have mild to moderate erectile dysfunction. This medicine also works best when you take it an hour before sex on an empty stomach. As with sildenafil, a high-fat meal or alcohol keep the body from absorbing it as quickly. Vardenafil usually works for 4 to 5 hours. Its effects might last longer if you have mild to moderate ED. A newer form of the medicine that dissolves on the tongue might work faster than the pill that you swallow.